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Microglial responses to CSF1 overexpression do not …
WebJan 14, 2024 · January 14, 2024. We refer to an article pointedly titled “CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages” in PNAS ( 1 ). This Brief Report addresses a straw man. Thirty years of studies on CSF1 signaling in peripheral populations, assessed via small-molecule ... Webcolony-stimulating factor 1 (CSF1) by a small minority of neoplastic cells leads to the recruitment of CSF1 receptor (CSF1R)-expressing macrophages, resulting in the formation of tumor mass11. This encourages the clinical application of CSF1R inhibitors in PVNS therapy with satisfactory outcomes yielded13-16. CSF1 is a daft cahersiveen
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